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DNA Helix

Cofund on Biotechnologies

Innovation for Europe – life science meets market application


Methyl Transferases for the Functional Diversification of Bioactives

Logo BioDiMet

Coordinator: Dr. Ulf Hanefeld, Delft University of Technology, HES, The Netherlands

Fraunhofer IGB, REC, Germany
University College London, HES, United Kingdom
University of Freiburg, HES, Germany
Ben-Gurion University of the Negev, HES, Israel
GlaxoSmithKline, LE, United Kingdom
Universidad Nacional de Quilmes, HES, Argentina

Group photo BioDiMet

Source: Dr. Michael Richter / Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB


Project Abstract

BioDiMet aims to develop a robust biocatalytic methyltransferase toolbox for selective synthesis of novel bioactives in an industrial setting. BioDiMet applies smart enzyme cascade reactions involving S-adenosyl-L-methionine (SAM)-dependent methyltransferases (MTs). This will lead to novel products with new functional properties for healthcare.

BioDiMet is funded by the ERA CoBioTech  partners:  SGCTeIp, BMBF, CSO-MOH, NWO, UKRI-BBSRC, UKRI-InnovateUK and co-funded by the European Union.

Project Start: April 2018  Duration: 36 months  
Project Budget:  Total Cost: 2.421.000 Euro, Funding: 1.911.000 Euro

Project Website:

HES – higher education sector – university
REC – research organisation
LE – large enterprise