Engineering microbial communities for the conversion of lignocellulose into medium-chain carboxylates
Coordinator: Prof. dr. Thomas Walther, Technische Universität Dresden, HES, Germany
SYNBIOMET project aims at developing a microbial fermentation process to produce 2,4-dihydroxybutyric acid (DHB), which is a precursor of the methionine analogon 2-hydroxy-4-(methylthio)butyrate (HMTB). Since DHB is not a natural metabolite in life cells, we will implement a synthetic metabolic pathway by combining modern enzyme engineering concepts and strain engineering. Research project's approach will enable a more sustainable, sugar-based production of HMTB which, at present, is exclusively produced from fossil resources.
Project Start: June 2021 Duration: 36 months
Project Budget: Total Cost: 1.522.000 Euro, Funding: 1.029.000 Euro
HES – higher education sector – university
REC – research organisation
SME – small and medium-sized enterprise