Investigating large scale bioreactor effects in microbial application
Coordinator: Prof. Dr. Marco Oldiges, Forschungszentrum Jülich GmbH, Institute of Bio- and Geosciences, IBG-1:Biotechnology, REC, Germany
Puratos NV/SA, Group Research and Services Enzymes, LE, Belgium
Gymetrics France SAS, R&D, SME, France
Technische Universität Berlin,Chair of Bioprocess Engineering, HES, Germany
Center of Food and Fermentation Technologies, R&D, REC, Estonia
In the ScaleApp project we address next generation design of scale-down bioreactor by smart combination of powerful CFD with innovative process analytical technology. Tailor-made scale down bioreactor setups will be validated and evaluated for their potential to facilitate bioprocess scale up. Our improvements in the design of scale-down bioreactor models and their predictive application at early-stages of strain engineering and bioprocess development, will allow critical decisions at the level of the lab-scale rather than at the level of production scale to reduce risk of failure and do more reliable estimation of bioprocess development times for current or new innovative products and processes from health care, food and feed as well as chemistry sector.
ScaleApp is funded by the ERA CoBioTech partners: SPW-Research, ETAg, ANR, BMBF and co-funded by the European Union.
Project Start: July 2018 Duration: 36 months
Project Budget: Total Cost: 2.720.000 Euro, Funding: 1.693.000 Euro
Project Website: https://www.fz-juelich.de/scaleapp/EN/Home/home_node.html
HES – higher education sector – university
REC – research organisation
LE – large enterprise
SME – small and medium-sized enterprise